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Modiodal Drogue
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Modiodal Drogue
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L'acГ©tylcholine est un neurotransmetteur essentiel et est nГ©cessaire au fonctionnement normal du systГЁme nerveux central. Le modafinil a Г©tГ© commercialisГ© pour la premiГЁre fois en France en 1981. Le modafinil semble agir en agissant sur la dopamine et en modulant les zones du cerveau impliquГ©es dans le cycle du sommeil. Il a Г©tГ© dГ©montrГ© que le modafinil provoque des effets secondaires similaires Г ceux d'autres stimulants. La dose recommandГ©e de Modafinil est de 300 mg, Г prendre 1 Г 4 heures avant le coucher. En plus de ses indications approuvГ©es, Modafinil est approuvГ© dans de nombreux autres pays pour le traitement de la somnolence diurne excessive rГ©sultant d'une condition mГ©dicale. Modiodal Drogue Le modafinil peut ГЄtre considГ©rГ© comme un traitement de l'insomnie, en particulier s'il rГ©sulte des effets secondaires d'une condition mГ©dicale sous-jacente. Il peut ГЄtre pris tel que prescrit ou occasionnellement lorsqu'il est nГ©cessaire de simplement rester Г©veillГ© tout en faisant des choses comme rester debout toute la nuit pour travailler ou Г©tudier. Le modafinil a Г©galement Г©tГ© Г©tudiГ© chez les enfants et les jeunes adultes atteints de trouble dГ©ficitaire de l'attention avec hyperactivitГ© (TDAH). Chaque comprimГ©, dose et injection est connu sous le nom commercial de la sociГ©tГ© pharmaceutique qui le produit. Un autre essai a trouvГ© une amГ©lioration similaire de la vigilance et de l'Г©veil de 9,6 heures Г la fin de la journГ©e aprГЁs 200 mg de Modafinil chez les personnes atteintes de narcolepsie. En 2002, il a Г©tГ© recommandГ© pour le traitement des troubles du sommeil liГ©s au travail postГ©. ГЂ des doses plus Г©levГ©es, il est plus susceptible de causer des problГЁmes de tension artГ©rielle, de l'insomnie et d'autres effets mГ©dicamenteux. ГЂ certaines doses, il a Г©tГ© rapportГ© qu'il amГ©liore la cognition. Le modafinil est utilisГ© pour traiter des patients de tous Гўges. Le modafinil stimule le systГЁme nerveux central, produisant une augmentation de l'Г©veil, de la vigilance et une rГ©duction de la somnolence. Le modafinil est notamment prescrit pour le traitement de la somnolence diurne excessive dans la narcolepsie, dans laquelle le mГ©dicament est pris pour corriger la somnolence diurne excessive et pour gГ©rer les symptГґmes liГ©s Г la perturbation du sommeil. Il a Г©galement Г©tГ© notГ© que le modafinil bloque en fait les effets de l'adГ©nosine sur les rГ©cepteurs de l'adГ©nosine A2A en bloquant l'effet de l'adГ©nosine sur les rГ©cepteurs A2A et en empГЄchant le rГ©cepteur de transfГ©rer son message Г la cellule induisant l'Г©veil. Ces effets favorisant l'Г©veil peuvent se faire via l'amГ©lioration des effets inhibiteurs descendants de la noradrГ©naline. Le modafinil est Г©galement approuvГ© pour le traitement de la somnolence diurne associГ©e Г l'apnГ©e obstructive du sommeil.
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