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Nootropique Pharmacie
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Le modafinil a Г©tГ© dГ©couvert dans les annГ©es 1970 Г l'UniversitГ© de Montpellier en France. Cela inclut la sГ©rotonine, qui joue un rГґle important dans la rГ©gulation de l'humeur et de l'Г©veil. Cela amГ©liore la biodisponibilitГ© du mГ©dicament dans le sang. Le modafinil est Г©galement suggГ©rГ© pour augmenter l'appГ©tit. Il a Г©galement Г©tГ© dГ©montrГ© qu'il augmente le nombre de micro-Г©veils du sommeil Г ondes lentes, un signe d'Г©veil ou de consolidation du sommeil. ГЂ des doses plus Г©levГ©es, il est plus susceptible de causer des problГЁmes de tension artГ©rielle, de l'insomnie et d'autres effets mГ©dicamenteux. Nootropique Pharmacie Le modafinil est utilisГ© pour traiter les personnes atteintes d'un trouble du sommeil appelГ© narcolepsie. Le modafinil agit principalement en augmentant les niveaux de deux produits chimiques du cerveau, la dopamine et l'acГ©tylcholine, de sorte que la Food and Drug Administration des Г‰tats-Unis affirme qu'il agit comme un stimulant. Son partenaire pharmaceutique amГ©ricain est Indivior, qui le commercialise sous la marque Provigil et les ventes internationales sont gГ©rГ©es par Galen Laboratories, qui a obtenu les droits de la sociГ©tГ© pharmaceutique britannique Indivior. Dans la littГ©rature scientifique, le modafinil est dГ©crit comme un activateur d'Г©veil et est chimiquement classГ© comme un N-benzyl-2-acГ©tamide. Les effets du modafinil durent jusqu'Г huit heures aprГЁs la prise d'une dose. La demi-vie apparente moyenne est de 2,8 heures. Le nom chimique du modafinil est 7-(benzhydrylsulfinyl)1,2-dihydro-2,2-dimГ©thyl-1-pyrrolidinone. Il est actif lorsqu'il est consommГ© et s'est avГ©rГ© influencer plusieurs rГ©cepteurs dans le cerveau, y compris la dopamine, la sГ©rotonine et l'adГ©nosine, avec des effets variables. C'est la libГ©ration contrГґlГ©e de Modafinil qui est utile pour augmenter l'Г©veil jusqu'Г la journГ©e, sans les effets secondaires dГ©sagrГ©ables tels que les maux de tГЄte dont certains utilisateurs se plaignent avec le Modafinil Г libГ©ration immГ©diate. ГЂ cet Г©gard, le modafinil est un agent noradrГ©nergique qui agit sur des rГ©cepteurs noradrГ©nergiques spГ©cifiques dans le locus ceruleus, la zone du cerveau qui rГ©gule l'Г©veil. Le modafinil est Г©galement utilisГ© par les participants Г la recherche pour les aider Г rester Г©veillГ©s pendant les tests cognitifs.
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