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Modiodal Modafinil
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Modiodal Modafinil
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Le CYP2C19 a un rГґle mineur dans le mГ©tabolisme du modafinil. L'AMA a annoncГ© en mars 2012 qu'elle autoriserait Г nouveau le modafinil comme somnifГЁre. Il est important de noter que le modafinil n'est pas le seul psychostimulant associГ© Г une augmentation des niveaux de dopamine dans le cerveau. Le mГ©dicament peut ГЄtre pris en une dose de 200 Г 400 mg, qui serait efficace pendant 24 heures ou plus. Le modafinil Г libГ©ration contrГґlГ©e est un agent inducteur d'Г©veil. Modiodal Modafinil Le modafinil, ainsi que d'autres stimulants, agit en augmentant la quantitГ© de dopamine libГ©rГ©e dans le cerveau. Le modafinil Г libГ©ration modifiГ©e est un comprimГ© pelliculГ© mou, soluble, destinГ© Г une administration orale une fois par jour. Ces neurotransmetteurs agissent en augmentant les niveaux de dopamine, de noradrГ©naline et de sГ©rotonine dans le cerveau. Le modafinil est un puissant stimulant des neurones dopaminergiques et un inhibiteur sГ©lectif de la recapture de la dopamine par la fente synaptique. Une Г©tude a rГ©vГ©lГ© que les patients prenant du modafinil affichaient une dГ©croissance plus lente de l'activitГ© cГ©rГ©brale, mesurГ©e par tomographie par Г©mission de positrons, par rapport aux tГ©moins sains. Le modafinil est bien tolГ©rГ©, avec des effets secondaires possibles, notamment des maux de tГЄte, des troubles du sommeil et des nausГ©es. Il peut Г©galement ГЄtre utilisГ© comme stimulant cognitif pour ceux qui souffrent de "brouillard cГ©rГ©bral". Il est Г©galement vendu comme somnifГЁre, mГЄme si le mГ©dicament est connu pour causer de l'insomnie. Une fois que le cerveau a Г©tГ© protГ©gГ© de la privation d'oxygГЁne, le modafinil se lie aux rГ©cepteurs de la dopamine sur les neurones voisins, en particulier les rГ©cepteurs D2. Il est disponible dans le commerce sous les noms Alertec (France), Armodafinil (SuГЁde), Catapres (Allemagne), Cognadil (Allemagne) et Modavia (SuГЁde), entre autres. Une poudre cristalline blanche Г blanc cassГ© qui est soluble dans un petit volume de DMSO et d'Г©thanol, et relativement insoluble dans l'eau froide.
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10-26-2023, 06:47 AM
(This post was last modified: 10-26-2023, 07:47 AM by wyrmrider.)
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10-26-2023, 07:48 AM
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10-26-2023, 08:49 AM
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