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Modafinil En Ligne Sans Ordonnance
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Modafinil En Ligne Sans Ordonnance
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Aux Г‰tats-Unis, il s'agit d'un mГ©dicament approuvГ© pour le traitement de la somnolence excessive associГ©e aux troubles du sommeil liГ©s au travail postГ© et pour le traitement de la somnolence associГ©e Г l'apnГ©e obstructive du sommeil. Cette diminution de la quantitГ© de GABA se traduit par une diminution de l'effet inhibiteur des neurones GABAergiques sur les autres neurones. Le modafinil, la forme prodrogue synthГ©tisГ©e chimiquement du d-modafinil, un stimulant de type amphГ©tamine, a Г©tГ© dГ©veloppГ© Г l'origine pour le traitement de la narcolepsie. Dans les Г©tudes animales, il a Г©tГ© dГ©montrГ© que le Modafinil augmente les substances chimiques du cerveau associГ©es Г l'Г©veil. Le modafinil est mГ©tabolisГ© Г 95 % par le foie. Il est Г©galement utilisГ© dans les situations de perte de sommeil rГ©currente qui surviennent pendant le travail postГ©. BrevetГ© par Eve Parmelee des laboratoires de recherche chimique Hydrus et licenciГ© Г Purdue Pharma, le mГ©dicament a d'abord Г©tГ© Г©tudiГ© chez l'homme par des mГ©decins de leur clinique Г Paris. Modafinil En Ligne Sans Ordonnance Il a Г©tГ© approuvГ© par la Food and Drug Administration (FDA) pour le traitement de la narcolepsie en 1998. Il est Г©galement approuvГ© par la FDA pour certaines conditions mГ©dicales, notamment le traitement de la somnolence excessive associГ©e Г la narcolepsie chez les enfants. Il subit une N-dГ©salkylation et une N-dГ©salkylation du cycle pipГ©razine, suivies d'une hydroxylation aromatique du fragment Г©thylamino. On pense qu'il amГ©liore l'Г©veil en augmentant les catГ©cholamines cГ©rГ©brales. Le modafinil reste dans le corps jusqu'Г 24 heures et est signalГ© comme entraГ®nant des effets pouvant durer jusqu'Г 24 heures. Les stimulants du SNC augmentent l'Г©veil, l'attention et/ou l'irritabilitГ© et sont utilisГ©s pour traiter la somnolence due Г la narcolepsie, les troubles du sommeil liГ©s au travail postГ© et l'apnГ©e obstructive du sommeil. Les effets secondaires du modafinil comprennent des maux de tГЄte, des troubles du sommeil et des nausГ©es. Le modafinil 200 mg ne fournit en moyenne que quelques heures de sommeil supplГ©mentaire, tandis que 400 mg fournit jusqu'Г 40 heures d'Г©veil supplГ©mentaire. L'avantage idГ©al est une amГ©lioration de l'Г©veil sans compromettre le sommeil normal. Au moment d'Г©crire ces lignes, le modafinil n'a pas de versions gГ©nГ©riques. Le modafinil est principalement un antagoniste des rГ©cepteurs О±1-adrГ©nergiques, mais peut Г©galement bloquer l'activitГ© des rГ©cepteurs de la sГ©rotonine et de la dopamine.
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10-26-2023, 01:11 AM
(This post was last modified: 10-26-2023, 01:16 AM by wyrmrider.)
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