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Modiodal Drogue
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Modiodal Drogue
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Une découverte de Bailes et al. Il a été démontré que le modafinil se lie au récepteur de la dopamine D2, et cette interaction entre le modafinil et le récepteur de la dopamine D2 peut expliquer en partie ses effets sur l'éveil, la cognition et la vigilance. La sérotonine, la norépinéphrine et la dopamine sont les principaux neurotransmetteurs responsables du sommeil et de l'éveil. Si aucune instruction n'est donnée, arrêtez de prendre le modafinil et contactez votre pharmacien ou votre médecin dès que possible. Les comprimés de modafinil doivent être avalés entiers avec un verre d'eau. Des doses de 400 à 600 mg sont recommandées dans la narcolepsie. Le modafinil réduit la durée d'activité de l'acétylcholine et augmente la durée de repos. Modiodal Drogue Il a été développé pour la première fois dans les années 1970 par le neuroscientifique français Michel Jouvet et les laboratoires Lafon. Le modafinil est un analogue de l'amphétamine. Des doses multiples peuvent avoir les mêmes effets secondaires qu'une seule dose importante. Il est hautement métabolisé dans le foie, où il est converti en l'énantiomère R du modafinil (R-Modafinil). Au Royaume-Uni, son nom de marque est Provision. On estime que le modafinil a une demi-vie de 5 à 6 heures. Les neurotransmetteurs dopaminergiques sont impliqués dans plusieurs types de fonctions, notamment la fonction motrice, l'humeur, la motivation, la cognition et l'attention. Cela a également amélioré la capacité de garder l'attention et de se concentrer sur les tâches. Le modafinil aide à bloquer la libération d'une substance chimique naturelle appelée sérotonine, qui est l'une des substances chimiques qui contrôlent la somnolence. Le modafinil serait métabolisé par l'isoenzyme 3A4 du cytochrome hépatique P450 (CYP). Comme l'amphétamine, le modafinil augmente les niveaux de sérotonine et supprime la recapture de la sérotonine.
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