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Modiodal Drogue
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Modiodal Drogue
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Il a Г©tГ© approuvГ© pour la premiГЁre fois par la FDA en 1998 pour le traitement de la narcolepsie ou des troubles du sommeil liГ©s au travail postГ©. La dose suggГ©rГ©e de modafinil pour une personne de 400 Г 500 kg est de 100 Г 200 mg pris une heure avant le coucher, bien que cela puisse devoir ГЄtre ajustГ© en fonction du poids du patient. La demi-vie du modafinil, comprise entre 12 et 15 heures, est similaire Г celle d'autres stimulants tels que les amphГ©tamines ou la mГ©thamphГ©tamine. La cafГ©ine bloque les rГ©cepteurs de l'adГ©nosine. La dГ©cision d'utiliser le modafinil doit ГЄtre prise avec prudence. Bien que le modafinil ait Г©tГ© un stimulant largement utilisГ© pour augmenter la vigilance, certains effets secondaires sont associГ©s Г sa prise. Le modafinil est un mГ©dicament d'ordonnance qui peut bГ©nГ©ficier Г ceux qui souffrent de troubles du sommeil courants. Modiodal Drogue Une Г©tude suggГЁre que le modafinil cible le systГЁme noradrГ©nergique. La qualitГ© du sommeil autodГ©clarГ©e s'est amГ©liorГ©e significativement plus chez les patients prenant du modafinil que dans le groupe placebo. Le mГ©canisme d'action du modafinil est similaire Г celui de l'amphГ©tamine. Le modafinil peut Г©galement provoquer des hallucinations. Dans la plupart des cas, les effets durent environ 8 Г 12 heures et il faut jusqu'Г 90 minutes pour quitter la circulation sanguine. Le modafinil est disponible en tant que mГ©dicament gГ©nГ©rique. Il peut ГЄtre avantageux d'utiliser le modafinil avec prudence chez les personnes atteintes d'affections pouvant augmenter la frГ©quence cardiaque. L'utilisation la plus courante du modafinil est le traitement de la somnolence diurne excessive. D'autres formes de traitement ont Г©tГ© essayГ©es, mais aucune ne s'est rГ©vГ©lГ©e plus efficace dans les essais cliniques. Les exigences posologiques varient selon les patients, selon la forme de modafinil qu'ils prennent. C'est un inhibiteur actif, sГ©lectif et rГ©versible du transporteur de la dopamine (DA) et du transporteur de la noradrГ©naline (NE). Il se prend gГ©nГ©ralement sous forme de comprimГ© de 200 mg en doses fractionnГ©es, le plus souvent le matin.
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