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Nootropique Pharmacie
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sur les rats. Le modafinil et son mГ©tabolite N-desmГ©thyl modafinil traversent facilement la barriГЁre hГ©mato-encГ©phalique et se distribuent dans le liquide cГ©phalo-rachidien. Il n'est pas clair si l'utilisation pendant la grossesse est sans danger. Le modafinil est utilisГ© pour traiter la somnolence excessive causГ©e par la narcolepsie et les troubles du sommeil liГ©s au travail postГ©. Il agit Г©galement comme un agent neuroprotecteur et a des actions antidГ©pressives et antipsychotiques. Il a Г©galement Г©tГ© dГ©montrГ© qu'il augmente le nombre de micro-Г©veils du sommeil Г ondes lentes, un signe d'Г©veil ou de consolidation du sommeil. Nootropique Pharmacie Le modafinil peut ГЄtre administrГ© par voie orale ou nasale. Le modafinil peut rГ©duire la somnolence dans le cerveau pendant huit Г 12 heures. La dose habituelle de Modafinil pour le traitement de la maladie de Parkinson est de 200 Г 400 mg/jour. ГЂ un moment donnГ©, les 400 mg avaient des prix de dГ©tail de 66 $ par comprimГ©. Aux Г‰tats-Unis, oГ№ le modafinil est une substance contrГґlГ©e de l'annexe IV, il a Г©tГ© commercialisГ© pour une utilisation hors AMM afin d'amГ©liorer l'Г©veil. Lorsqu'il est pris selon les directives, Modafinil produit des amГ©liorations marquГ©es de l'Г©veil et de la vigilance. Des rГ©actions dermatologiques plus graves peuvent survenir chez les personnes prГ©sentant des prГ©dispositions gГ©nГ©tiques et plus frГ©quemment chez les patients pГ©diatriques. Le taux de diffusion de la dopamine dans le noyau accumbens du cerveau est augmentГ© par le modafinil. Une dose de 200 mg est gГ©nГ©ralement prise pour les troubles psychiatriques plus graves, tandis que 200 mg Г 400 mg sont gГ©nГ©ralement prises pour la narcolepsie. L'Г©tude a montrГ© une augmentation significative de la vitesse de traitement de l'information. Les patients sont encouragГ©s Г augmenter leur dose jusqu'Г ce qu'ils atteignent un niveau de vigilance appropriГ© et doivent ГЄtre avertis de le faire lentement.
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