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Acheter Modafinil
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Acheter Modafinil
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Dans la narcolepsie, les cellules hypocrГ©tines du cerveau sont dГ©ficientes, une carence qui peut provoquer un endormissement rapide et des hallucinations. Le mГ©dicament est disponible sous forme de comprimГ© et d'injection Г action prolongГ©e (formulation injectable Г libГ©ration prolongГ©e, Г©galement appelГ©e antimuscarinique). La cafГ©ine augmente le mГ©tabolisme du modafinil, mais n'augmente pas l'exposition. Il inhibe la recapture de l'acГ©tylcholine et de la dopamine dans certaines zones du cerveau, ainsi que la liaison aux rГ©cepteurs de l'histamine H1 et H2, la liaison Г la mГ©latonine et les rГ©cepteurs muscariniques humains recombinants de l'acГ©tylcholine M2. Le modafinil semble agir en agissant sur la dopamine et en modulant les zones du cerveau impliquГ©es dans le cycle du sommeil. Il existe de nombreuses autres formes de Modafinil disponibles, dont une avec une forme Г libГ©ration prolongГ©e pour une utilisation une fois par semaine. L'imagerie par rГ©sonance magnГ©tique fonctionnelle (IRMf) chez les personnes souffrant d'insomnie a montrГ© que le mГ©dicament rГ©duisait l'activitГ© du systГЁme limbique, impliquГ© dans la rГ©gulation de l'excitation. Acheter Modafinil Il est Г©galement utilisГ© hors AMM pour certaines dГ©pressions et parfois pour l'insomnie. Le modafinil gГ©nГ©rique n'est pas une copie exacte du mГ©dicament de marque et il existe certaines diffГ©rences entre les deux. Un comitГ© consultatif de la FDA en 2013 a trouvГ© des preuves Г l'appui de son utilisation comme amГ©liorateur de performance diurne, avec la mise en garde qu'il pourrait ne pas ГЄtre efficace chez les personnes souffrant de troubles du sommeil. La dopamine est un neurotransmetteur, et l'une de ses fonctions est de favoriser l'Г©veil. Le modafinil est disponible en comprimГ©s de 120 mg et 200 mg. Il est Г©galement disponible sous les marques Modalert et Modavigil en Australie, en Inde, en CorГ©e et aux Philippines. Une Г©tude suggГЁre que le modafinil augmente les niveaux de sГ©rotonine, mais cela reste Г confirmer. Il n'agit pas comme la dextroamphГ©tamine ou le mГ©thylphГ©nidate, mais il ne crГ©e pas de dГ©pendance physique et ne provoque pas de dГ©pendance. Le temps nГ©cessaire pour voir tout type d'effet est infГ©rieur Г 1 heure. Il est rapidement distribuГ© dans tout le corps avec des concentrations plasmatiques maximales entre 1 et 4 heures aprГЁs l'ingestion. Il est gГ©nГ©ralement pris au besoin. Le modafinil agit en inhibant les transporteurs DA et NE, bloquant la recapture de ces neurotransmetteurs dans les axones.
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