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Modiodal Drogue
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Le modafinil est Г©galement utilisГ© pour traiter le trouble du rythme circadien du sommeil, une condition qui survient gГ©nГ©ralement chez les travailleurs postГ©s oГ№ il y a une perturbation du rythme circadien ou du rythme naturel du sommeil. Une dose plus lente de 200 mg une fois par jour est recommandГ©e pour les patients pГ©diatriques et les jeunes adultes. Le mГ©dicament Modafinil est un stimulant du SNC dГ©livrГ© uniquement sur ordonnance (annexe IV). Il a un effet direct sur l'excitabilitГ© des zones corticales, conduisant Г l'Г©veil. Le modafinil peut Г©galement inhiber l'enzyme monoamine oxydase dans le cerveau, ce qui peut prolonger les effets des deux neurotransmetteurs, mais il n'a pas Г©tГ© dГ©montrГ© de maniГЁre concluante que cela se produit rГ©ellement chez l'homme. Modiodal Drogue Les effets secondaires indГ©sirables sont similaires Г ceux d'autres stimulants, notamment des palpitations, des difficultГ©s respiratoires, de la colГЁre et de l'agitation. Le modafinil est un composГ© inorganique, un composГ© organique constituГ© de deux Г©lГ©ments qui sont liГ©s ensemble dans le cadre d'un composГ© ou d'une molГ©cule plus grande. Il existe des rapports contradictoires quant aux effets de l'utilisation chronique de cafГ©ine et de modafinil. Il est disponible en trois dosages : 100 mg, 200 mg et 400 mg, et peut ГЄtre pris dans un certain nombre de formulations, y compris un comprimГ© Г croquer et un comprimГ©. L'approbation amГ©ricaine concernait "le traitement de la somnolence excessive associГ©e Г la narcolepsie et Г l'hypersomnie idiopathique". Modafinil a Г©tГ© dГ©veloppГ© pour traiter la narcolepsie. Aux Г‰tats-Unis, une dose unique de 100 mg de Provigil coГ»te 179,20 USD et une dose unique de 50 mg de Modalert coГ»te 112,40 USD. La formulation originale de Modafinil, Ritalin-SR, a un dГ©but d'action rapide (moins d'une heure) et est prise cinq fois par jour. L'administration frГ©quente n'est pas recommandГ©e et la dose recommandГ©e est de 200 mg. Le modafinil est librement soluble dans l'Г©thanol et insoluble dans l'eau. Des problГЁmes peuvent survenir lors de la prise ou de l'arrГЄt du mГ©dicament. Cela signifie que si vous commencez Г vous sentir trop somnolent pendant la journГ©e, vous pouvez en prendre plus. Le modafinil a Г©tГ© dГ©couvert dans les annГ©es 1970 Г l'UniversitГ© de Montpellier en France.
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