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Modiodal Drogue

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Modiodal Drogue
#1
Une association a Г©tГ© Г©tablie entre le modafinil et des rГ©actions dermatologiques graves, y compris la possibilitГ© qu'il puisse provoquer une Г©ruption cutanГ©e connue sous le nom de syndrome de Stevens-Johnson. Le modafinil n'est pas recommandГ© pendant la grossesse et la quantitГ© de mГ©dicament utilisГ©e peut devoir ГЄtre ajustГ©e pour les patientes souffrant de problГЁmes hГ©patiques ou rГ©naux. P. Les effets secondaires possibles comprennent des maux de tГЄte, des troubles du sommeil, de la somnolence, de la nervositГ©, de l'irritabilitГ©, des nausГ©es, des Г©tourdissements et de la diarrhГ©e. Le mГ©canisme exact reste inconnu, mais on pense qu'il agit sur la dopamine et module les zones du cerveau impliquГ©es dans le cycle du sommeil. La dose recommandГ©e est de 100 Г  200 mg Г  la fois, jusqu'Г  400 mg par jour. Modiodal Drogue De plus, on pense que le modafinil diminue les niveaux de sГ©rotonine dans les ganglions de la base, qui sont responsables de la motivation et du mouvement. Le modafinil agit en stimulant les neurones producteurs de dopamine du cerveau. Le modafinil peut augmenter le risque de certaines interactions mГ©dicamenteuses. Il est structurellement liГ© Г  la noradrГ©naline et Г  la phГ©nylГ©thylamine. Le modafinil est vendu sous forme de prescription et en vente libre et est accompagnГ© d'une Г©tiquette d'avertissement. Modafinil est disponible en diffГ©rentes concentrations. Il s'agit d'un stimulant du systГЁme nerveux qui a Г©tГ© utilisГ© hors AMM comme prГ©tendu activateur cognitif pour amГ©liorer l'Г©veil dans des Г©tudes animales et humaines, mais les preuves de son efficacitГ© en tant qu'activateur cognitif restent anecdotiques. Le modafinil est disponible en tant que mГ©dicament gГ©nГ©rique. Les patients prenant du modafinil avant le coucher peuvent avoir besoin de rГ©duire la quantitГ© totale prise ou d'Г©viter de prendre du modafinil juste avant le coucher. Il n'aura pas d'effets permanents. La mГ©ta-analyse a Г©galement suggГ©rГ© que le modafinil pourrait ne pas produire d'amГ©lioration cognitive chez les personnes sous les effets de l'alcool ou d'autres dГ©presseurs. Le modafinil est un stimulant et fonctionne donc en augmentant la dГ©charge des neurones rГ©cepteurs de la dopamine post-synaptiques, provoquant la libГ©ration de plus de dopamine dans le systГЁme dopaminergique mГ©solimbique. Il existe Г©galement une pilule combinГ©e modafinil-dexamphГ©tamine gГ©nГ©rique, qui est une combinaison du modafinil catГ©cholamine favorisant l'Г©veil et de la dextroamphГ©tamine amphГ©tamine favorisant l'Г©veil. Le modafinil peut Г©galement empГЄcher la dГ©gradation d'un autre neurotransmetteur, la dopamine. Le mГ©canisme d'action spГ©cifique est inconnu, mais le modafinil peut agir sur les zones du cerveau impliquГ©es dans le sommeil.

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#2
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