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Nootropique Pharmacie
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Cela peut Г©galement rendre plus difficile l'endormissement au coucher chez les personnes atteintes de narcolepsie. Cependant, il n'y a aucune preuve scientifique Г l'appui. On ne sait pas si le modafinil affecte les malformations congГ©nitales, le dГ©veloppement fЕ“tal ou les fЕ“tus qui ont Г©tГ© exposГ©s au modafinil en laboratoire. Il existe Г©galement plusieurs types diffГ©rents de ce mГ©dicament, notamment le citrate de modafinil et le modafinil sans saveur. Environ 20 % sont excrГ©tГ©s sous forme de modafinil non mГ©tabolisГ©. Un effet secondaire rare est des pensГ©es ou des actions suicidaires. En gГ©nГ©ral, les personnes qui fument ou qui ont des antГ©cГ©dents de maladie du foie ou des reins peuvent ГЄtre plus sensibles au modafinil. Deux mГ©canismes diffГ©rents contribuent probablement Г l'inhibition de la libГ©ration de mГ©latonine par le modafinil : Le premier mГ©canisme implique l'inhibition de la transmission neuronale de la lumiГЁre. Le modafinil agit Г©galement sur les rГ©cepteurs de la sГ©rotonine, mais on ne sait pas si cela augmente la neurotransmission de la sГ©rotonine. Des Г©tudes ont indiquГ© que l'interaction du modafinil avec les rГ©cepteurs de l'adГ©nosine A2A dans le cerveau pourrait ГЄtre responsable de sa capacitГ© Г bloquer les effets de l'adГ©nosine, son prГ©curseur, qui est libГ©rГ© pendant l'Г©veil, et pourrait expliquer pourquoi il a des effets hors cible. Il n'a pas Г©tГ© dГ©terminГ© si Modafinil est sГ»r Г utiliser pendant la grossesse. Le modafinil est Г©galement disponible sous forme de comprimГ© pelliculГ©, de comprimГ© dispersible, de formulation de comprimГ© pelliculГ© et de suspension. Nootropique Pharmacie Le modafinil a une courte demi-vie. Le modafinil soulage Г©galement les symptГґmes des troubles du sommeil tels que les troubles du sommeil liГ©s au travail postГ© et l'apnГ©e obstructive du sommeil, en aidant Г augmenter la vigilance tout au long de la journГ©e. La majoritГ© des agents favorisant l'Г©veil stimulent les neurones du cortex prГ©frontal. Le modafinil diffГЁre des autres stimulants par rapport au(x) neurotransmetteur(s) ciblГ©(s). Il semble fonctionner en activant les centres cГ©rГ©braux qui produisent la vigilance. L'alprazolam, l'ingrГ©dient actif de XANAX, est Г©galement un composant de certains types de modafinil. Il peut Г©galement fonctionner en stimulant l'acГ©tylcholine, la sГ©rotonine, l'histamine et la noradrГ©naline. Le modafinil n'est pas non plus recommandГ© aux personnes ayant des antГ©cГ©dents de dГ©pression, car il peut induire ou aggraver les symptГґmes. La vente de modafinil est illГ©gale en Chine, au Japon, en Australie et dans plusieurs territoires amГ©ricains. Chez certains patients, l'effet du modafinil semble ГЄtre similaire Г celui des amphГ©tamines. Le modafinil est un mГ©dicament qui peut interagir avec d'autres mГ©dicaments.
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